The oldest Roman Catholic church in London, St. Etheldreda's stands on Ely Place, off Charterhouse Street, at Holborn Circus. Built in 1251, it was mentioned by the Bard in both Richard II and Richard III. A survivor of the Great Fire of 1666, the church and the area surrounding it were the property of the diocese of the city of Ely, in the days when many bishops had Episcopal houses in London, as well as in the cathedral cities in which they held their sees. The property still has a private road, with impressive iron gates and a lodge for the gatekeeper. Six elected commissioners manage the church and area.

St. Etheldreda, whose name is sometimes shortened to St. Audrey, was a 7th-century king's daughter who left her husband and established an abbey on the Isle of Ely. St. Etheldreda's has a distinguished musical tradition, with the 11am mass on Sunday sung in Latin. Other masses are on Sunday at 9am, Monday through Friday at 8am and 1pm, and Saturday at 9:30am. Lunch, with a varied choice of hot and cold dishes, is served Monday through Friday from 11:30am to 2pm in the Pantry.