Even if you don't plan on spending the day in Hyde Park, you'll pass through the neighborhood on your way to one of Chicago's most popular tourist attractions. The massive Museum of Science and Industry is the granddaddy of interactive museums, with some 2,000 exhibits. You should plan on spending at least a couple of hours here, and a comprehensive visit can take all day, especially if you catch an Omnimax movie while you're here. Although it's quite a distance from the rest of Chicago's tourist attractions, it's easy enough to get here without a car; your best options are the no. 6 Jeffrey Express bus or the Metra Electric train from downtown (the no. 10 bus runs from downtown to the museum's front entrance during the summer).

While the museum is constantly adding new exhibits to cover the latest scientific breakthroughs, you shouldn't miss certain tried-and-true exhibits that have been here for years and epitomize the museum for Chicagoans. The U-505, a German submarine that was captured in 1944 and brought to the museum 10 years later, brings home the claustrophobic reality of underwater naval life. The full-scale Coal Mine, which dates back to 1934, now incorporates modern mining techniques into the exhibit -- but the best part is the simulated trip down into a dark, mysterious mine. Get to these exhibits quickly after the museum opens because they attract amusement-park-length lines during the day.

Kids who love planes, trains, and automobiles shouldn't miss All Aboard the Silver Streak, a refurbished Burlington Pioneer Zephyr train with on-board interactive exhibits; the massive model train exhibit that makes up The Great Train Story; or Take Flight, an aviation exhibit featuring a full-size 727 airplane that revs up its engines and replays the voice recordings from a San Francisco-Chicago flight periodically throughout the day. Computer addicts should be entranced by Networld, which offers a flashy immersion into the Internet (with plenty of interactive screens). More low-tech -- but fascinating -- is the giant walk-through model of the human heart. Well-designed educational exhibits include AIDS: The War Within (which was the 1st permanent museum exhibit on the immune system and HIV) and Reusable City, which teaches children ecological tips with implements that they might find in their own backyard. Older children with a creative streak will enjoy Enterprise, which lets visitors take on the role of CEO for a day as they immerse themselves in the goings-on of a virtual company.

And, not to be sexist, but girls (myself included) love Colleen Moore's Fairy Castle, a lavishly decorated miniature palace filled with priceless treasures (yes, those are real diamonds and pearls in the chandeliers). The castle is hidden away on the lower level. Also tucked away in an inconspicuous spot -- along the Blue stairwell between the Main Floor and the Balcony -- are the Human Body Slices, actual slivers of human cadavers that are guaranteed to impress teenagers in search of something truly gross.

A major newer addition to the museum is the Henry Crown Space Center, where the story of space exploration is documented in copious detail, highlighted by a simulated space-shuttle experience through sight and sound at the center's five-story Omnimax Theater. The theater offers double features on the weekends; call for show times.

When you've worked up an appetite, you can visit one of the museum's five restaurants, including a Pizza Hut and an ice-cream parlor, and there are also two gift shops. Allow 3 hours.